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簡(jiǎn)要描述：The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-bind
產(chǎn)品型號(hào)：bs-3041R廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-02-26訪 問(wèn) 量： 42產(chǎn)品分類
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